Invitrogen™ MLK3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544553

Catalog No. PIPA544553

Description

Peptide sequence: PVGQRSAKSP RREEEPRGGT VSPPPGTSRS APGTPGTPRS PPLGLISRPR Sequence homology: Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

MAP3K11 (MLK3) is a serine/threonine kinase that activates both the p38 MAP kinase and c-Jun kinase pathways. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.

Specifications

• Antigen: MLK3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAP3K11
• Gene Alias: 2610017K16Rik; MAP3K11; MEKK11; MGC17114; mitogen activated protein kinase kinase kinase 11; mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Mlk3; MLK-3; protein-tyrosine kinase PTK1; PTK1; RHOE; SH3 domain-containing proline-rich kinase; SPRK; Src-homology 3 domain-containing proline-rich kinase
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4296
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q16584
• Gene Symbols: MAP3K11
• Immunogen: Synthetic peptide directed towards the middle region of human MAP3K11.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG