Invitrogen™ MLL4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540760

Catalog No. PIPA540760

Description

Peptide sequence: WAGPRVQRGR GRGRGRGWGP SRGCVPEEES SDGESDEEEF QGFHSDEDVA Sequence homology: Cow: 92%; Dog: 85%; Guinea Pig: 92%; Horse: 83%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%; Yeast: 91%.

This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.

Specifications

• Antigen: MLL4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KMT2B
• Gene Alias: 2610014H22Rik; ALL1-related protein; ALR; BC032281; BC058659; C430014K11Rik; CXXC10; histone-lysine N-methyltransferase 2B; histone-lysine N-methyltransferase 2B-like; histone-lysine N-methyltransferase 2D; histone-lysine N-methyltransferase MLL2; histone-lysine N-methyltransferase MLL4; HRX2; KIAA0304; Kmt2b; Kmt2d; LOC102550344; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2B; lysine (K)-specific methyltransferase 2B; lysine (K)-specific methyltransferase 2D; lysine methyltransferase 2B; lysine N-methyltransferase 2B; lysine N-methyltransferase 2D; mixed lineage leukemia 2; mixed lineage leukemia gene homolog 2; mKIAA0304; MLL1B; MLL2; MLL4; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4; myeloid/lymphoid or mixed-lineage leukemia 2; myeloid/lymphoid or mixed-lineage leukemia 4; myeloid/lymphoid or mixed-lineage leukemia protein 2; myeloid/lymphoid or mixed-lineage leukemia protein 4; Myeloid/lymphoid or mixed-lineage leukemia protein 4 homolog; trithorax homolog 2; trithorax homologue 2; TRX2; Wbp7; WBP-7; WW domain binding protein 7; WW domain-binding protein 7
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 9757
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9UMN6
• Gene Symbols: KMT2B
• Immunogen: Synthetic peptide directed towards the N-terminal of human MLL4 (aa 84-133).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG