Invitrogen™ MLL4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116906

Catalog No. PIPA5116906

Description

Positive Samples: THP-1, Mouse testis, Mouse brain Immunogen sequence: GLSDEDYEIL SGLPDSVLYT CGPCAGAAQP RWREALSGAL QGGLRQVLQG LLSSKVVGPL LLCTQCGPDG KQLHPGPCGL QAVSQRFEDG HYKSVHSFME DMVGILMRHS EEGETPDRRA GGQMKGLLLK LLESAFGWFD AHDPKYWRRS TRLPNGVLPN AVLPPSLDHV YAQWRQQEPE TPESGQPPGD PSAAFQGKDP A.

This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.

Specifications

• Antigen: MLL4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KMT2B
• Gene Alias: 2610014H22Rik; ALL1-related protein; ALR; BC032281; BC058659; C430014K11Rik; CXXC10; histone-lysine N-methyltransferase 2B; histone-lysine N-methyltransferase 2B-like; histone-lysine N-methyltransferase 2D; histone-lysine N-methyltransferase MLL2; histone-lysine N-methyltransferase MLL4; HRX2; KIAA0304; Kmt2b; Kmt2d; LOC102550344; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2B; lysine (K)-specific methyltransferase 2B; lysine (K)-specific methyltransferase 2D; lysine methyltransferase 2B; lysine N-methyltransferase 2B; lysine N-methyltransferase 2D; mixed lineage leukemia 2; mixed lineage leukemia gene homolog 2; mKIAA0304; MLL1B; MLL2; MLL4; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4; myeloid/lymphoid or mixed-lineage leukemia 2; myeloid/lymphoid or mixed-lineage leukemia 4; myeloid/lymphoid or mixed-lineage leukemia protein 2; myeloid/lymphoid or mixed-lineage leukemia protein 4; Myeloid/lymphoid or mixed-lineage leukemia protein 4 homolog; trithorax homolog 2; trithorax homologue 2; TRX2; Wbp7; WBP-7; WW domain binding protein 7; WW domain-binding protein 7
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 102550344, 75410, 9757
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.81 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O08550, Q9UMN6
• Gene Symbols: KMT2B
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1370-1570 of human KMT2B (NP_0555421).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG