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Invitrogen™ MLLT1 Polyclonal Antibody
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Catalog No. PIPA5116821
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100 μL
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PIPA5116821 100 μL
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Catalog No. PIPA5116821 Supplier Invitrogen™ Supplier No. PA5116821
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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse thymus, Rat brain, Rat thymus Immunogen sequence: KTSKPHKVTK EHRERPRKDS ESKSSSKELE REQAKSSKDT SRKLGEGRLP KEEKAPPPKA AFKEPKMALK ETKLESTSPK G.

Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11;19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MLLT1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.03 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene MLLT1
Gene Accession No. Q03111
Gene Alias AA407901; BAM11; CTC-503J8.6; ENL; ENL/MLL fusion; leukemia-associated protein MLLT1; LTG19; MLL/ENL fusion protein; MLLT1; MLLT1 super elongation complex subunit; MLLT1, super elongation complex subunit; MLLT1/MLL fusion; myeloid/lymphoid or mixed lineage leukemia translocation to 1 homolog; myeloid/lymphoid or mixed lineage-leukemia translocation to 1 homolog; myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1; protein ENL; trithorax; YEATS domain-containing protein 1; YEATS1
Gene Symbols MLLT1
Host Species Rabbit
Immunogen Recombinant protein (or fragment)
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 301119, 4298, 64144
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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