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MLLT1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501572469
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50-157-2469 100 μL
50-157-2470 10 μL
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Catalog No. 50-157-2469 Supplier Bethyl Laboratories, Inc Supplier No. IHC00648
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, Gorilla, Northern white-cheeked gibbon and White-tufted-ear marmoset

Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11;19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.

Specifications

Antigen MLLT1
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene MLLT1
Gene Accession No. Q03111
Gene Alias CTC-503J8.6, ENL, ENL/MLL fusion, LTG19, MLL/ENL fusion protein, MLLT1/MLL fusion, myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 1, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1, YEATS domain-containing protein 1, YEATS1
Gene Symbols MLLT1
Host Species Rabbit
Immunogen Between 325 and 375
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4298
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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