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Invitrogen™ MLLT11 Polyclonal Antibody
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Catalog No. PIPA581879
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100 μL
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PIPA581879 100 μL
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Catalog No. PIPA581879 Supplier Invitrogen™ Supplier No. PA581879
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FWRMPIPELD LSELEGLGLS DTATYKVKDS SVGKMIGQAT AADQEKNPEG DGLLEYSTFN FWRAPIASIH SFEL Highest antigen sequence indentity to the following orthologs: Rat - 79%, Mouse - 83%.

The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MLLT11
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MLLT11
Gene Accession No. Q13015
Gene Alias AF1Q; AF1Q protein; AI839562; ALL1 fused gene from chromosome 1q; ALL1-fused gene from chromosome 1q; MLLT11; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11; protein AF1q; RGD1305525; Zfp692; zinc finger protein 692
Gene Symbols MLLT11
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MLLT11. Recombinant protein control fragment (Product #RP-93690).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10962
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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