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Invitrogen™ MLLT11 Polyclonal Antibody
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Catalog No. PIPA5103027
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100 μL
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PIPA5103027 100 μL
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Catalog No. PIPA5103027 Supplier Invitrogen™ Supplier No. PA5103027
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MLLT11.

The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MLLT11
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MLLT11
Gene Accession No. P97783, Q13015, Q5M971
Gene Alias AF1Q; AF1Q protein; AI839562; ALL1 fused gene from chromosome 1q; ALL1-fused gene from chromosome 1q; MLLT11; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11; protein AF1q; RGD1305525; Zfp692; zinc finger protein 692
Gene Symbols MLLT11
Host Species Rabbit
Immunogen A synthesized peptide derived from human MLLT11(Accession Q13015), corresponding to amino acid residues M1-T35.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10962, 295264, 56772
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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