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Invitrogen™ MMACHC Polyclonal Antibody
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Catalog No. PIPA521798
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100 μL
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PIPA521798 100 μL
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Catalog No. PIPA521798 Supplier Invitrogen™ Supplier No. PA521798
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Raji, mouse brain. Predicted reactivity: Mouse (85%), Rat (86%), Pig (91%), Rhesus Monkey (97%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The exact function of the MMACHC protein is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMACHC
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene MMACHC
Gene Accession No. Q9CZD0, Q9Y4U1
Gene Alias 1810037K07Rik; cblC; Cyanocobalamin reductase (cyanide-eliminating); methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria; methylmalonic aciduria and homocystinuria type C protein; Methylmalonic aciduria and homocystinuria type C protein homolog; methylmalonic aciduria cblC type, with homocystinuria; Mmachc; RGD1310806; RP11-291L19.3
Gene Symbols MMACHC
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human MMACHC. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25974, 313520, 67096
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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