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Invitrogen™ MMACHC Polyclonal Antibody
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Catalog No. PIPA555599
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100 μL
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PIPA555599 100 μL
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Catalog No. PIPA555599 Supplier Invitrogen™ Supplier No. PA555599
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EIIADYEVHP NRRPKILAQT AAHVAGAAYY YQRQDVEADP WGNQRISGVC IHPRFGGWFA IRGVVLLPGI EVPDLPPRKP HDCVPT Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 90%.

The exact function of the MMACHC protein is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMACHC
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MMACHC
Gene Accession No. Q9Y4U1
Gene Alias 1810037K07Rik; cblC; Cyanocobalamin reductase (cyanide-eliminating); methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria; methylmalonic aciduria and homocystinuria type C protein; Methylmalonic aciduria and homocystinuria type C protein homolog; methylmalonic aciduria cblC type, with homocystinuria; Mmachc; RGD1310806; RP11-291L19.3
Gene Symbols MMACHC
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MMACHC. Recombinant protein control fragment (Product #RP-94200).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25974
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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