Invitrogen™ MMACHC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555599

Catalog No. PIPA555599

Description

Immunogen sequence: EIIADYEVHP NRRPKILAQT AAHVAGAAYY YQRQDVEADP WGNQRISGVC IHPRFGGWFA IRGVVLLPGI EVPDLPPRKP HDCVPT Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 90%.

The exact function of the MMACHC protein is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.

Specifications

• Antigen: MMACHC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MMACHC
• Gene Alias: 1810037K07Rik; cblC; Cyanocobalamin reductase (cyanide-eliminating); methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria; methylmalonic aciduria and homocystinuria type C protein; Methylmalonic aciduria and homocystinuria type C protein homolog; methylmalonic aciduria cblC type, with homocystinuria; Mmachc; RGD1310806; RP11-291L19.3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25974
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y4U1
• Gene Symbols: MMACHC
• Immunogen: Recombinant protein corresponding to Human MMACHC. Recombinant protein control fragment (Product #RP-94200).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG