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  5. Tocris Bioscience™ MMG 11

Tocris Bioscience™ MMG 11
GREENER_CHOICE

Catalog No. 685810
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

TLR2 antagonist

MMG 11 is a TLR2 antagonist (IC50 values are in the range 1.7 - 5.7 μM). Exhibits selectivity for TLR2 over TLR4, TLR5, TLR7/8 and TLR9. Reduces TLR2-mediated cytokine secretion from PBMCs. MMG 11 preferentially inhibits TLR2/1- over TLR2/6-mediated NK-κB activation (IC50 values are 0.87 and 7.4 μM, respectively).

Specifications

Chemical Name or Material Ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate
CAS 313254-94-3
Quantity 10 mg
Target Toll-like Receptor Antagonists
Molecular Formula C15H14O7
Formula Weight 1414
Purity 97%
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