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  5. Tocris Bioscience™ MMG 11

Tocris Bioscience™ MMG 11
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Catalog No. 685850
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Catalog No. Quantity
68-585-0 50 mg
68-581-0 10 mg
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Catalog No. 68-585-0 Supplier Tocris Bioscience™ Supplier No. 6858/50
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Description

TLR2 antagonist

MMG 11 is a TLR2 antagonist (IC50 values are in the range 1.7 - 5.7 μM). Exhibits selectivity for TLR2 over TLR4, TLR5, TLR7/8 and TLR9. Reduces TLR2-mediated cytokine secretion from PBMCs. MMG 11 preferentially inhibits TLR2/1- over TLR2/6-mediated NK-κB activation (IC50 values are 0.87 and 7.4 μM, respectively).

Specifications

Chemical Name or Material Ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate
CAS 313254-94-3
Quantity 50 mg
Target Toll-like Receptor Antagonists
Molecular Formula C15H14O7
Formula Weight 5252
Purity 97%
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