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Epredia™ Lab Vision™ MMP-1 (Collagenase-1) Ab-6, Rabbit Polyclonal Antibody

Catalog No. RB1536R1 Shop All Epredia Products
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Description

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with the Epredia™ MMP-1 (Collagenase-1) Ab-6, Rabbit Polyclonal Antibody.

Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading connective tissue components. Imbalanced secretion of certain MMP or disturbances in the differential control of MMP by tissue inhibitor of MMPs (TIMPs) are implicated in the invasive potential of malignant tumors. Interstitial collagenase (MMP-1), 72kDa gelatinase A/type IV collagenase (MMP-2), and 92kDa gelatinase B/type IV collagenase (MMP-9) dissolve extracellular matrix (ECM) and may initiate and promote angiogenesis.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human. Does not react with cow. Others not known.

Epitope: Middle region of MMP-1

Immunogen: A synthetic peptide from the middle region of the human MMP-1

Molecular Weight: 52kDa (unglycosylated) and 57kDa (glycosylated) species of proform of MMP-1 plus 42kDa (unglycosylated) and 47kDa (glycosylated) active form of MMP-1

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells; Placenta; Bladder, breast, ovarian, colon CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen MMP-1 (Collagenase-1) Ab-6
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
Formulation Ready-to-use for IHC (UVLP)
Host Species Rabbit
Immunogen A synthetic peptide from the middle region of the human MMP-1
Quantity 1 mL
Regulatory Status RUO
Research Discipline Proteases And Inhibitors
Primary or Secondary Primary
Target Species Human
Form Prediluted
Isotype IgG
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