Invitrogen™ MMP10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120847

Catalog No. PIPA5120847

Description

Positive test controls include: BT-474, MCF7, U-251MG, M21. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space. Immunogen sequence: PLYNSFTELA QFRLSQDDVN GIQSLYGPPP ASTEEPLVPT KSVPSGSEMP AKCDPALSFD AISTLRGEYL FFKDRYFWRR SHWNPEPEFH LISAFWPSLP SYLDAAYEVN SRDTVFIFKG NEFWAIRGNE VQAGYPRGIH TLGFPPTIRK IDAAVSDKEK KKTYFFAADK YWRFDENSQS MEQGFPRLIA DDFPGVEPKV DAVLQAFGFF YFFSGSSQFE FDPNARMVTH ILKSNSWLHC.

MMP10 belongs to the matrix metalloproteinase family, and is generally secreted in its pro form, which is further modified by extracellular proteinases. As a metalloproteinase, MMP10 requires zinc and calcium as cofactors for activity. It is involved in the activation of pro-collagenase, catabolism of collagen, degradation of fibronectin, and tissue remodeling. In humans, the gene MMP10 located on chromosome 11.

Specifications

• Antigen: MMP10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MMP10
• Gene Alias: AV377895; matrix metallo protease; matrix metallopeptidase 10; matrix metallopeptidase 10 (stromelysin 2); matrix metalloprotease 10; matrix metalloproteinase 10; matrix metalloproteinase 10 (stromelysin 2); matrix metalloproteinase-10; MMP; Mmp10; MMP-10; MMPs; SL-2; STMY2; stromelysin 2; stromelysin-2; Transformation-associated protein 34A; transin 2; transin-2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 117061, 17384, 4319
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 3.93 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O55123, P07152, P09238
• Gene Symbols: MMP10
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 237-476 of human MMP10 (NP_0024161).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG