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MMP13 Monoclonal Antibody (LIPCO IID1), Invitrogen™

Catalog No. PIMA514247
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500 μL
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PIMA514247 500 μL
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Catalog No. PIMA514247 Supplier Thermo Scientific Supplier No. MA514247
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Description

Mouse Monoclonal Antibody

MA5-14247 targets MMP-13 (Collagenase-3) (Rat) in IF, IP, and WB applications and shows reactivity with mouse and Rat samples. The MA5-14247 immunogen is rat MMP-13 from BC-1 cells.

MMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMP13
Applications Immunocytochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone LIPCO IID1
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene MMP13
Gene Accession No. P23097, P33435
Gene Alias cb1034; Clg; CLG3; Collagenase; collagenase 3; collagenase 3a; matrix metalloproteinase 13a; collagenase-1; Collagenase3; Collagenase-3; collagenase-3 precursor; interstitial collagenase; MANDP1; matrix metallo protease; matrix metallopeptidase 13; matrix metallopeptidase 13 (collagenase 3); matrix metallopeptidase 13a; matrix metallopeptidase 13a (collagenase 3); matrix metalloproteinase 13; matrix metalloproteinase 13 (collagenase 3); matrix metalloproteinase-13; matrix metalloproteinase-13; MMP-13; interstitial protein; MMP; Mmp1; MMP13; MMP-13; mmp13 protein; mmp13a; MMPLg; MMPLh; MMPs; Procollagenase 3; UMRCASE; ZFMMP13
Gene Symbols MMP13
Host Species Mouse
Immunogen Rat MMP-13 from BC-1 cells
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171052, 17386
Target Species Mouse, Rat
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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