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MMP13 Monoclonal Antibody (OTI1F1), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA506692

Encompass_Preferred

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Catalog No. 50-167-6721


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Description

Description

MMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.
Specifications

Specifications

MMP13
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P45452
MMP13
Human recombit protein fragment corresponding to amino acids 104-471 of human MMP13 produced in HEK293T cell.
100 μL
Primary
Human
Antibody
IgG1
Immunocytochemistry, Immunofluorescence, Western Blot
OTI1F1
Unconjugated
MMP13
CLG3, MANDP1, MDST, MMP-13
Mouse
Affinity Chromatography
RUO
4322
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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