MMP14 Mouse anti-Human, Clone: 3A6, Bioss

Catalog No.	Quantity
50-197-9804	100 μL

Catalog No. 50-197-9804 Supplier Bioss Supplier No. BSM51028M

Description

Mouse Monoclonal Antibody

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP′s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Specifications

• Antigen: MMP14
• Applications: Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: 3A6
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
• Gene: MMP14
• Gene Accession No.: P50281
• Gene Alias: AI325305; cb386; EC 3.4.24.80; matrix metallo protease; matrix metallopeptidase 14; matrix metallopeptidase 14 (membrane-inserted); matrix metallopeptidase 14a (membrane-inserted); matrix metalloproteinase 14 (membrane-inserted); matrix metalloproteinase 14 (membrane-inserted) alpha; matrix metalloproteinase 14 membrane-inserted; matrix metalloproteinase 14, membrane-inserted; matrix metalloproteinase 14a (membrane-inserted); Matrix metalloproteinase-14; membrane type 1 metalloprotease; membrane type 1-matrix metalloproteinase; Membrane type 1-MMP; Membrane-type matrix metalloproteinase 1; membrane-type matrix metalloproteinase 1 alpha; Membrane-type-1 matrix metalloproteinase; MMP; MMP14; MMP-14; mmp14a; MMPs; MMP-X MT-MMP; MMP-X1; MT1MMP; MT1-MMP; MT1-MMP-alpha; Mtmmp; MT-MMP; MT-MMP 1; MT-MMP MT1-MMP; MTMMP1; MT-MMP-1; MT-MMPalpha; sabe; sb:cb386; type 1 matrix metalloprotease 14; WNCHRS; wu:fb72b09; zMT-MMPalpha; zMT-MMP-alpha
• Gene Symbols: MMP14
• Host Species: Mouse
• Immunogen: This MMP14 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 470-499 amino acids from the C-terminal region of human MMP14.
• Purification Method: Protein G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4323
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgM