Invitrogen™ MMP14 Recombinant Rabbit Monoclonal Antibody (6T7L3)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535044

Catalog No. PIMA535044

Description

Immunogen sequence: GAEIKANVRR KRYAIQGLKW QHNEITFCIQ NYTPKVGEYA TYEAIRKAFR VWESATPLRF REVPYAYIRE GHEKQADIMI FFAEGFHGDS TPFDGEGGFL A.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Specifications

• Antigen: MMP14
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P50281, P53690, Q10739
• Gene Symbols: MMP14
• Immunogen: Synthetic peptide.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 6T7L3
• Conjugate: Unconjugated
• Gene: MMP14
• Gene Alias: AI325305; cb386; EC 3.4.24.80; matrix metallo protease; matrix metallopeptidase 14; matrix metallopeptidase 14 (membrane-inserted); matrix metallopeptidase 14a (membrane-inserted); matrix metalloproteinase 14 (membrane-inserted); matrix metalloproteinase 14 (membrane-inserted) alpha; matrix metalloproteinase 14 membrane-inserted; matrix metalloproteinase 14, membrane-inserted; matrix metalloproteinase 14a (membrane-inserted); matrix metalloproteinase-14; matrix metalloproteinase-14a; membrane type 1 metalloprotease; membrane type 1-matrix metalloproteinase; Membrane type 1-MMP; membrane-type matrix metalloproteinase 1; membrane-type matrix metalloproteinase 1 alpha; membrane-type-1 matrix metalloproteinase; MMP; MMP14; MMP-14; mmp14a; MMPs; MMP-X MT-MMP; MMP-X1; MT1MMP; MT1-MMP; MT1-MMP-alpha; Mtmmp; MT-MMP; MT-MMP 1; MT-MMP MT1-MMP; MTMMP1; MT-MMP-1; MT-MMPalpha; sabe; sb:cb386; type 1 matrix metalloprotease 14; WNCHRS; wu:fb72b09; zMT-MMPalpha; zMT-MMP-alpha
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17387, 4323, 81707
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid