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Invitrogen™ MMP17 Polyclonal Antibody
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Catalog No. PIPA132162
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400 μL
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PIPA132162 400 μL
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Catalog No. PIPA132162 Supplier Invitrogen™ Supplier No. PA132162
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Human hepatocarcinoma tissue. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMP17
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Gene MMP17
Gene Accession No. Q9ULZ9
Gene Alias matrix metallo protease; matrix metallopeptidase 17; matrix metallopeptidase 17 (membrane-inserted); matrix metalloproteinase 17; matrix metalloproteinase 17 (membrane-inserted); matrix metalloproteinase-17; membrane type-4 matrix metalloproteinase; membrane-type matrix metalloproteinase 4; Membrane-type-4 matrix metalloproteinase; MMP; Mmp17; MMP-17; MMPs; MT4MMP; MT4-MMP; MT-MMP 4; MTMMP4
Gene Symbols MMP17
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 391-420 amino acids from the Central region of human MMP17.
Purification Method Ammonium sulfate precipitation
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4326
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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