Invitrogen™ MMP17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA132162

Catalog No. PIPA132162

Description

Recommended positive controls: Human hepatocarcinoma tissue. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.

Specifications

• Antigen: MMP17
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MMP17
• Gene Alias: matrix metallo protease; matrix metallopeptidase 17; matrix metallopeptidase 17 (membrane-inserted); matrix metalloproteinase 17; matrix metalloproteinase 17 (membrane-inserted); matrix metalloproteinase-17; membrane type-4 matrix metalloproteinase; membrane-type matrix metalloproteinase 4; Membrane-type-4 matrix metalloproteinase; MMP; Mmp17; MMP-17; MMPs; MT4MMP; MT4-MMP; MT-MMP 4; MTMMP4
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 4326
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: Q9ULZ9
• Gene Symbols: MMP17
• Immunogen: KLH conjugated synthetic peptide between 391-420 amino acids from the Central region of human MMP17.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov