Invitrogen™ MMP17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116980

Catalog No. PIPA5116980

Description

Positive Samples: SW480, RAW264.7, Mouse testis, Rat testis Immunogen sequence: IMRPYYQGPV GDPLRYGLPY EDKVRVWQLY GVRESVSPTA QPEEPPLLPE PPDNRSSAPP RKDVPHRCST HFDAVAQIRG EAFFFKGKYF WRLTRDRHLV SLQPAQMHRF WRGLPLHLDS VDAVYERTSD HKIVFFKGDR YWVFKDNNVE EGYPRPVSDF SLPPGGIDAA FSWAHNDRTY FFKDQLYWRY DDHTRHMDPG YPAQSPLWRG VPSTLDDAMR WSDGASYFFR GQEYWKVLDG ELEVAPGYPQ STARDWLVCG DSQADGSVAA GVDAAEGPRA PPGQHDQSRS EDGYEVCSCT S.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.

Specifications

• Antigen: MMP17
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MMP17
• Gene Alias: matrix metallo protease; matrix metallopeptidase 17; matrix metallopeptidase 17 (membrane-inserted); matrix metalloproteinase 17; matrix metalloproteinase 17 (membrane-inserted); matrix metalloproteinase-17; membrane type-4 matrix metalloproteinase; membrane-type matrix metalloproteinase 4; Membrane-type-4 matrix metalloproteinase; MMP; Mmp17; MMP-17; MMPs; MT4MMP; MT4-MMP; MT-MMP 4; MTMMP4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23948, 288626, 4326
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2.2 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9R0S3, Q9ULZ9
• Gene Symbols: MMP17
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 265-565 of human MMP17 (NP_0572394).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG