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Invitrogen™ MMP17 Polyclonal Antibody
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Catalog No. PIPA5116980
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100 μL
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PIPA5116980 100 μL
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Catalog No. PIPA5116980 Supplier Invitrogen™ Supplier No. PA5116980
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Description

Rabbit Polyclonal Antibody

Positive Samples: SW480, RAW264.7, Mouse testis, Rat testis Immunogen sequence: IMRPYYQGPV GDPLRYGLPY EDKVRVWQLY GVRESVSPTA QPEEPPLLPE PPDNRSSAPP RKDVPHRCST HFDAVAQIRG EAFFFKGKYF WRLTRDRHLV SLQPAQMHRF WRGLPLHLDS VDAVYERTSD HKIVFFKGDR YWVFKDNNVE EGYPRPVSDF SLPPGGIDAA FSWAHNDRTY FFKDQLYWRY DDHTRHMDPG YPAQSPLWRG VPSTLDDAMR WSDGASYFFR GQEYWKVLDG ELEVAPGYPQ STARDWLVCG DSQADGSVAA GVDAAEGPRA PPGQHDQSRS EDGYEVCSCT S.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMP17
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene MMP17
Gene Accession No. Q9R0S3, Q9ULZ9
Gene Alias matrix metallo protease; matrix metallopeptidase 17; matrix metallopeptidase 17 (membrane-inserted); matrix metalloproteinase 17; matrix metalloproteinase 17 (membrane-inserted); matrix metalloproteinase-17; membrane type-4 matrix metalloproteinase; membrane-type matrix metalloproteinase 4; Membrane-type-4 matrix metalloproteinase; MMP; Mmp17; MMP-17; MMPs; MT4MMP; MT4-MMP; MT-MMP 4; MTMMP4
Gene Symbols MMP17
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 265-565 of human MMP17 (NP_0572394).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23948, 288626, 4326
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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