MMP2 Mouse anti-Human, Clone: 6E3F8, Abnova™

Catalog No.	Quantity
89-934-564	100 μL

Catalog No. 89-934-564 Supplier Abnova Corporation Supplier No. MAB12299

Description

Mouse monoclonal antibody raised against human MMP2.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

• Antigen: MMP2
• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Classification: Monoclonal
• Clone: 6E3F8
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against human MMP2.
• Dilution: Immunohistochemistry (1:50-1:100) Western Blot (1:200-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.09% sodium azide)
• Gene Alias: CLG4/CLG4A/MMP-II/MONA/TBE-1
• Gene Symbols: MMP2
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human MMP2.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4313
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2b κ