MMP2 Mouse anti-Human, Mouse, Clone:2B11E6, Abnova™

Catalog No.	Quantity
89-333-546	100 μg

Catalog No. 89-333-546 Supplier Abnova Corporation Supplier No. MAB17268

Description

Mouse monoclonal antibody raised against recombinant human MMP2.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP′s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

• Antigen: MMP2
• Applications: ELISA, Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: 2B11E6
• Conjugate: Unconjugated
• Description: matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunohistochemistry
  Immunocytochemistry
  Flow Cytometry (1:200-1:400)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: MMP2
• Gene Alias: CLG4, CLG4A, MMP-II, MONA, TBE-1
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acid 9-140 of human MMP2 from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 4313
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1