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Invitrogen™ MMP23 (Cleaved Tyr79) Polyclonal Antibody
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Catalog No. PIPA537434
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PIPA537434 100 μL
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Catalog No. PIPA537434 Supplier Invitrogen™ Supplier No. PA537434
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 37 and 44 kDa. Purity is >95% by SDS-PAGE.

Matrix metalloproteinases (MMPs) are highly homologous Zn2+ endopeptidases involved in extracellular matrix breakdown. MMP mediated extracellular remodeling occurs in normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, including arthritis and metastasis. MMP-23 exhibits sequence similarity with most MMPs, but displays a difference in domain structure. The MMP-23 protein contains prepro-, catalytic, cysteine-rich, Interleukin-1 receptor-related and proline-rich domains. Lacking a recognizable signal sequence, MMP-23 has a short prodomain. In addition, MMP-23 contains a single cysteine residue that can be part of the cysteine-switch mechanism operation for maintaining enzyme latency. MMP-23 is a membrane-anchored glycoprotein with type II topology. Subcellular localization is predominantly perinuclear.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMP23 (Cleaved Tyr79)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene MMP23B
Gene Accession No. O75900
Gene Alias Femalysin; matrix metallopeptidase 23A (pseudogene); matrix metallopeptidase 23B; matrix metalloproteinase 22; matrix metalloproteinase 23B; matrix metalloproteinase in the female reproductive tract; matrix metalloproteinase-21; Matrix metalloproteinase-22; matrix metalloproteinase-23; Matrix metalloproteinase-23, soluble form; MIFR; MIFR-1; MMP 23; MMP21; MMP-21; MMP22; MMP-22; MMP23; MMP-23; MMP23A; MMP23B; soluble form
Gene Symbols MMP23B
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 51-100 of human MMP-23.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8510, 8511
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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