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Invitrogen™ MMP24 Polyclonal Antibody
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Catalog No. PIPA5100202
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Quantity:
100 μL
Catalog No. Quantity
PIPA5100202 100 μL
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Catalog No. PIPA5100202

Supplier: Invitrogen™ PA5100202

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MMP24.

All cells within tissues are surrounded by an extracellular matrix (ECM) giving the tissues shape and structure. The ECM is constantly being remodeled and constant communication is maintained between cells through this matrix. Secreted proteins, termed matrix metalloproteinases (MMPs), are involved in the modulation of cell-matrix interactions. MMPs are Zn (2+)-binding endopeptidases that degrade various components of the ECM. MMPs are enzymes implicated in normal and pathologic tissue remodeling processes, wound healing, angiogenesis, and tumor invasion. These enzymes are very potent when active, and are associated with extracellular space inhibitors called TIMPs (tissue inhibitors of matrix metalloproteinases). TIMPs have been shown to block tumor cell invasion suggesting that they act as metastasis suppressor genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMP24
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MMP24
Gene Accession No. Q99PW6, Q9R0S2, Q9Y5R2
Gene Alias AU040325; matrix metallo protease; matrix metallopeptidase 24; matrix metallopeptidase 24 (membrane-inserted); matrix metalloproteinase 24; matrix metalloproteinase 24 (membrane-inserted); matrix metalloproteinase-21; Matrix metalloproteinase-24; membrane type 5-MMP; membrane-type 5 matrix metalloproteinase; membrane-type matrix metalloproteinase 5; Membrane-type-5 matrix metalloproteinase; MMP; Mmp21; MMP-21; Mmp24; MMP-24; MMP25; MMPs; MT5MMP; Mt5-mmp; MT-MMP 5; MTMMP5; MT-MMP5; Processed matrix metalloproteinase-24; RP4-614O4.10
Gene Symbols MMP24
Host Species Rabbit
Immunogen A synthesized peptide derived from human MMP24(Accession Q9Y5R2), corresponding to amino acid residues F442-K492.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10893, 17391, 83513
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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