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Invitrogen™ MMP28 Polyclonal Antibody
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Catalog No. PIPA125309
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25 μg
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PIPA125309 25 μg
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Catalog No. PIPA125309 Supplier Invitrogen™ Supplier No. PA125309
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Description

Rabbit Polyclonal Antibody

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Epilysin, also known as matrix metalloproteinase-28 (MMP-28), is a secreted protein that belongs to the peptidase M10A family. Matrix metalloproteinase proteins are responsible for the breakdown of the extracellular matrix which is important for normal physiological processes such as tissue remodeling, reproduction and embryonic development. Epilysin is produced by proliferating keratinocytes and is responsible for mediating the degradation of casein. Its expression is upregulated in response to injury of the skin suggesting that Epilysin may be involved in tissue repair and homeostasis. In addition, Epilysin may function predominantly in the nervous system. Incubation of Epilysin with rat embryonic brain tissue results in the degradation of myelin proteins. In Xenopus, Epilysin localizes to nerves and is upregulated during neurulation. This suggests that Epilysin plays an evolutionarily conserved role in neural development and may be involved in modulating the axonal-glial extracellular environment.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMP28
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% sodium azide
Gene MMP28
Gene Accession No. Q9H239
Gene Alias D130023P12; Epilysin; matrix metallo protease; matrix metallopeptidase 28; matrix metallopeptidase 28 (epilysin); matrix metalloprotease MMP25; matrix metalloproteinase 28 (epilysin); matrix metalloproteinase-28; MM28; MMP; MMP25; MMP-25; Mmp28; MMP-28; MMPs; PRO4339; UNQ1893; UNQ1893/PRO4339
Gene Symbols MMP28
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the propeptide region of human matrix metalloproteinase-28.
Purification Method Antigen affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79148
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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