Invitrogen™ MMP27 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA125307

Catalog No. PIPA125307

Description

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Metalloproteinases (MMPs) are a family of proteins that are involved in the breakdown of the extracellular matrix during normal cellular events, including reproduction, tissue remodeling and embryonic development. MMPs are crucial in tumor invasion and building of metastatic formations because of their ability to degrade extracellular matrix proteins such as fibronectin, laminin, gelatins and/or collagen. MMP-27 (matrix metallopeptidase 27) is a 513 amino acid secreted protein that is expressed in B-cells. Belonging to the peptidase M10A family, MMP-27 contains four hemopexin-like domains, which is suggested to be involved in substrate recognition. MMP-27, along with other MMP family members, is associated with breast cancer development and tumor progression.

Specifications

• Antigen: MMP27
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MMP27
• Gene Alias: Gm180; matrix metallo protease; matrix metallopeptidase 27; matrix metalloprotease 27; matrix metalloproteinase 27; matrix metalloproteinase-27; MMP; MMP27; MMP-27; MMPs; UNQ2503/PRO5992
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64066
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% sodium azide
• Gene Accession No.: Q9H306
• Gene Symbols: MMP27
• Immunogen: Synthetic peptide corresponding to the hinge domain of human MMP-27.
• Quantity: 25 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov