Invitrogen™ MMP27 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564398

Catalog No. PIPA564398

Description

Immunogen sequence: FWPSLPADLQ AAYENPRDKI LVFKDENFWM IRGYAVLPDY PKSIHTLGFP GRVKKIDAAV CDKTTR Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 83%.

Metalloproteinases (MMPs) are a family of proteins that are involved in the breakdown of the extracellular matrix during normal cellular events, including reproduction, tissue remodeling and embryonic development. MMPs are crucial in tumor invasion and building of metastatic formations because of their ability to degrade extracellular matrix proteins such as fibronectin, laminin, gelatins and/or collagen. MMP-27 (matrix metallopeptidase 27) is a 513 amino acid secreted protein that is expressed in B-cells. Belonging to the peptidase M10A family, MMP-27 contains four hemopexin-like domains, which is suggested to be involved in substrate recognition. MMP-27, along with other MMP family members, is associated with breast cancer development and tumor progression.

Specifications

• Antigen: MMP27
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MMP27
• Gene Alias: Gm180; matrix metallo protease; matrix metallopeptidase 27; matrix metalloprotease 27; matrix metalloproteinase 27; matrix metalloproteinase-27; MMP; MMP27; MMP-27; MMPs; UNQ2503/PRO5992
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64066
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H306
• Gene Symbols: MMP27
• Immunogen: Recombinant protein corresponding to Human MMP27. Recombinant protein control fragment (Product #RP-104100).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov