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MMP7 Monoclonal Antibody (ID2), Invitrogen™

Catalog No. PIMA514215
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500 μL
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Catalog No. Quantity
PIMA514215 500 μL
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Catalog No. PIMA514215 Supplier Thermo Scientific Supplier No. MA514215

Description

Mouse Monoclonal Antibody

MA5-14215 targets MMP-7 (Matrilysin) in IF applications and shows reactivity with Human samples. The MA5-14215 immunogen is recombinant human matrilysin (PUMP-1).

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMP7
Applications Immunocytochemistry
Classification Monoclonal
Clone ID2
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene MMP7
Gene Accession No. P09237
Gene Alias HGNC:7174; MAT; Matrilysin; matrilysin, uterine; matrin; matrix metallo protease; matrix metallopeptidase 7; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7; Matrix metalloproteinase 7 (matrilysin); matrix metalloproteinase 7 (matrilysin, uterine); matrix metalloproteinase-7; MMP; MMP 7; MMP7; Mmp-7; MMP-7 protein; MMPs; MPMM; MPSL1; PUMP 1; Pump 1 protease; PUMP1; PUMP-1; pump-1 protease; uterine matrilysin; uterine metalloproteinase
Gene Symbols MMP7
Host Species Mouse
Immunogen Recombinant human matrilysin (PUMP-1)
Purification Method Protein A
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4316
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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