MMP7 Monoclonal Antibody (OTI3G7), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA804842

Catalog No. 50-168-0434

Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP′s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Specifications

• Antigen: MMP7
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P09237
• Gene Symbols: MMP7
• Immunogen: Human recombit protein fragment corresponding to amino acids 95-267 of human MMP7 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin)
• Clone: OTI3G7
• Conjugate: Unconjugated
• Gene: MMP7
• Gene Alias: MMP-7, MPSL1, PUMP-1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4316
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid