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Invitrogen™ MMP7 Polyclonal Antibody
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Catalog No. PIPA5119931
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100 μL
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PIPA5119931 100 μL
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Catalog No. PIPA5119931 Supplier Invitrogen™ Supplier No. PA5119931
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Description

Rabbit Polyclonal Antibody

Positive Control: A549 cell lysates, HT-29 cell lysate, A431 cell lysate, A549, human uterus tissue, HT-29. Subcellular Location: Extracellular matrix, Secreted.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMP7
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene MMP7
Gene Accession No. P09237
Gene Alias HGNC:7174; MAT; Matrilysin; matrilysin, uterine; matrin; matrix metallo protease; matrix metallopeptidase 7; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7; Matrix metalloproteinase 7 (matrilysin); matrix metalloproteinase 7 (matrilysin, uterine); matrix metalloproteinase-7; MMP; MMP 7; MMP7; Mmp-7; MMP-7 protein; MMPs; MPMM; MPSL1; PUMP 1; Pump 1 protease; PUMP1; PUMP-1; pump-1 protease; uterine matrilysin; uterine metalloproteinase
Gene Symbols MMP7
Host Species Rabbit
Immunogen Synthetic peptide within human MMP7 aa 220-267.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4316
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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