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  6. MMP9 (N-terminal) Rabbit anti-Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech 

MMP9 (N-terminal) Rabbit anti-Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech
SDP

Catalog No. 501726255 Shop All Proteintech Group Inc Products
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50-172-6255 150 μL
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Catalog No. 50-172-6255 Supplier Proteintech Group Inc Supplier No. 103752AP150UL
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Description

Rabbit Polyclonal Antibody

MMP9 (matrix metallopeptidase 9, GELB, CLG4B) is a matrix metalloproteinase, a family of zinc and calcium-dependent endopeptidases that degrade extracellular matrix proteins. MMP9 is secreted as a 92 kDa zymogen and cleavage of pro-MMP9 results in the active enzyme with a molecular weight of 82 kDa. MMP9 has a gelatin-binding domain consisting of three fibronectin type II units, a catalytic domain containing the zinc-binding site, a proline-rich type V collagen-homologous domain and a hemopexin-like domain. MMP9 is produced by monocytes, macrophages, neutrophils, keratinocytes, fibroblasts, osteoclasts and endothelial cells, and is involved in inflammatory responses, tissue remodeling, wound healing, tumor growth and metastasis. MMP9 is supplied by bone marrow-derived cells and contributes to skin carcinogenesis. Further, MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. Studies have shown that elevated MMP9 is associated with progression of idiopathic atrial fibrillation and aortic aneurysm.

Specifications

Antigen MMP9 (N-terminal)
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.27 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene MMP9
Gene Accession No. P14780, P41245, P50282
Gene Alias 92 kDa gelatinase, 92 kDa type IV collagenase, CLG4B, Gelatinase B, GELB, Matrix metalloproteinase 9, MMP 9, MMP9
Gene Symbols Mmp9
Host Species Rabbit
Immunogen MMP9 (N-terminal) Fusion Protein Ag0552
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17395, 406397, 4318, 81687
Target Species Human, Mouse, Rat, Zebrafish
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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