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MMRN1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989435
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Catalog No. Quantity
50-198-9435 100 μL
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Catalog No. 50-198-9435 Supplier Bioss Supplier No. BS9899R
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Description

Rabbit Polyclonal Antibody

Multimerin-1, also known as MMRN1, EMILIN-4 or ECM (endothelial cell multimerin), is a 1,228 amino acid secreted protein that contains one C1q domain, one EMI domain and one EGF-like domain. Synthesized in megakaryocytes and endothelial cells and present in liver, lung and placenta, Multimerin-1 exists as a multimeric structure composed of varying disulfide-linked multimers and functions as a carrier protein for platelet factors (specifically platelet factor V), playing a role in the stabilization and storage of factor V in platelets. In addition, Multimerin-1 acts as a ligand for select Integrins and may participate in extracellular matrix adhesion. Defects in the gene encoding Multimerin-1 that lead to Multimerin-1 deficiency are associated with autosomal dominant bleeding disorders due to platelet factor malfunction. Multiple isoforms of Multimerin-1 exist due to alternative splicing events.

Specifications

Antigen MMRN1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene MMRN1
Gene Accession No. Q13201
Gene Alias 155 kDa platelet multimerin; 4921530G03Rik; ECM; Elastin microfibril interface located protein 4; Elastin microfibril interfacer 4; EMILIN4; EMILIN-4; Endothelial cell multimerin; glycoprotein Ia*; GPIA*; MMRN; Mmrn1; multimerin 1; Multimerin-1; p155; p-155; Platelet glycoprotein Ia*
Gene Symbols MMRN1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human MMRN1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22915
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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