MMS21 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A304128AT

Catalog No. 50-156-6944

Description

The recommended shelf life for this product is 1 year from date of receipt.

MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.

Specifications

• Antigen: MMS21
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NSMCE2
• Gene Alias: C8orf36, MMS21, NSE2; E3 SUMO-protein ligase NSE2; MMS21 homolog; hMMS21; methyl methanesulfonate sensitivity gene 21; non-SMC element 2 homolog; non-structural maintece of chromosomes element 2 homolog
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 286053
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q96MF7
• Gene Symbols: NSMCE2
• Immunogen: Between 125 and 175
• Quantity: 10 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG