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MMS21 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501566944
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50-156-6944 10 μL
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Catalog No. 50-156-6944 Supplier Bethyl Laboratories, Inc Supplier No. A304128AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.

Specifications

Antigen MMS21
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene NSMCE2
Gene Accession No. Q96MF7
Gene Alias C8orf36, MMS21, NSE2; E3 SUMO-protein ligase NSE2; MMS21 homolog; hMMS21; methyl methanesulfonate sensitivity gene 21; non-SMC element 2 homolog; non-structural maintece of chromosomes element 2 homolog
Gene Symbols NSMCE2
Host Species Rabbit
Immunogen Between 125 and 175
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 286053
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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