Invitrogen™ MNT Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA541603

Catalog No. PIPA541603

Description

Peptide sequence: SIETLLEAAR FLEWQAQQQQ RAREEQERLR LEQEREQEQK KANSLARLAH Sequence homology: Cow: 93%; Dog: 93%; Horse: 80%; Human: 100%; Mouse: 93%; Pig: 80%; Rabbit: 93%; Rat: 93%; Yeast: 92%.

The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.

Specifications

• Antigen: MNT
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MNT
• Gene Alias: BHLHD3; Class D basic helix-loop-helix protein 3; MAD6; max binding protein; MAX network transcriptional repressor; max-binding protein MNT; Max-interacting protein; MNT; MNT, MAX dimerization protein; MXD6; Myc antagonist MNT; Protein ROX; Rox
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4335
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q99583
• Gene Symbols: MNT
• Immunogen: Synthetic peptide directed towards the N-terminal of human MNT (aa 2-51).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov