Invitrogen™ HCS DNA Damage Kit

Description

Includes

Kit contains sufficient reagents for performing two plates in a 96-well plate format.

Detects DNA damage and cytotoxicity

The HCS DNA Damage kit simultaneously and quantitatively measures two important cell-health parameters: DNA damage and cytotoxicity. DNA damage is detected using an antibody against phosphorylated H2AX (Ser139) which is induced in response to double-strand break (DSB) formation. To detect cytotoxicity, the Image-iT™ DEAD™ Green is an impermeant dye in healthy cells that becomes permeant when the plasma membrane of cells is compromised. Both indicators are amenable to fixation and permeabilization, thus allowing for multiplexing with other biomarkers of interest. The blue-fluorescent nuclear segmentation tool Hoechst 33342 is also included and stains DNA in both live and dead cells.

Cell Analysis, Cell Viability and Cytotoxicity, Cell Viability, Proliferation and Function

Order Info

Shipping Condition: Dry ice

Specifications

• Color: Orange, Blue, Green
• Content And Storage: The kit contains sufficient reagents for performing 2 plates in a 96-well plate format.
  Store at ≤-20°C, desiccate and protect from light.
• Detection Method: Fluorescence
• For Use With (Equipment): High Content Analysis Instrument
• Product Type: DNA Damage kit
• Dye Type: Alexa Fluor™ 555, Hoechst 33258
• Format: 96-well plate
• Product Line: Molecular Probes
• Quantity: 1 kit
• Shipping Condition: Dry Ice

For Research Use Only. Not for use in diagnostic procedures.