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Invitrogen™ Low Density Lipoprotein from Human Plasma, DiI complex (DiI LDL)
Description
Human low-density lipoprotein (LDL) is large protein complex (approx. 500,000 Da) that binds to a specific receptor on surface of vertebrate cells and delivers cholesterol via receptor-mediated endocytosis. Experiments to study LDL are typically performed by adding fluorescently labeled LDL to cultured cells and analyzing them by microscopy or flow cytometry. Alternatively fluorescently labeled LDL can be injected into test animals, and distribution of the label can be analyzed after the specified time period.
- Label (Ex/Em): Dil (554/571)
- Acetylated: No
- Amount: 200μL (1.0mg/mL
- Nonacetylated LDL products are shipped within two weeks of their preparation
- LDL containing unmodified apoprotein is used to study normal cholesterol delivery and internalization
- Applications for labeled LDL complexes include: Counting cell-surface LDL receptors, and analyzing their motion and clustering following internalization; Quantitating LDL receptor activity in fibroblasts (replacing the radiolabeled LDL assay); Investigating LDL expression and identifying LDL receptor deficiencies in various cell lines
Cell Analysis, Cell Cycle, Cell Structure, Cell Viability, Proliferation and Function, Endocytosis, Exocytosis and Phagocytosis, Lysosomes, Vacuoles
Order Info
Shipping Condition: Wet Ice
Specifications
Specifications
| Concentration | 1 mg⁄ml |
| Content And Storage | Store in refrigerator (2–8°C) and protect from light. |
| Detection Method | Fluorescence |
| Product Type | Supplement |
| Dye Type | Other Label(s) or Dye(s) |
| Form | Liquid |
| Quantity | 200 μL |
| Shipping Condition | Wet Ice |
Safety and Handling
For Research Use Only. Not for use in diagnostic procedures.
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