Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Cell Analysis Products
  4. Cell Based Assays
  5. Cell Function Reagents and Kits
  6. N7991

Invitrogen™ Newport Green™ DCF Diacetate, cell permeant

Catalog No. N7991
Encompass_Preferred
Change view
Click to view available options
Quantity:
1 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
N7991 1 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. N7991 Supplier Invitrogen™ Supplier No. N7991
Add to Cart
Edge
Add to Cart

missing translation for 'validMainframeMsg'

Description

Has moderate zinc-binding affinity (Kd for Zn2+ approximately 1μM) but is essentially insensitive to Ca2+.

The Newport Green™ DCF indicator has moderate zinc-binding affinity (Kd for Zn2+ ∼1 μM) but is essentially insensitive to Ca2+ (Kd for Ca2+ >100 μM), making this a valuable probe for detecting Zn2+ influx into neurons through voltage- or glutamate-gated channels. When used alongside dyes with dual Ca2+ / Zn2+ sensitivity such as fura-2 and mag-fura-2, Newport Green™ DCF provides confirmation that changes in Zn2+ levels, and not Ca2+ or Mg2+, are being detected. The response of Newport Green™ DCF to transition metals, including Zn, Mn, Fe, Co, Cu(I), Cu(II), Ni and Cd, has been characterized.

Newport Green™ PDX has a higher Zn2+ dissociation constant (Kd for Zn2+ ∼30 μM) and a larger Zn2+-free to Zn2+-saturated fluorescence intensity increase than the Newport Green™ DCF indicators.

Fluorescent Zinc Indicators Specifications:

  • Label (Ex/Em): Newport Green™ DCF (∼505/535 nm)
  • Kd (Zn2+) (in buffer): ∼1 μM
  • Lyophilized product may be dissolved in DMSO for use
  • Product is typically loaded into cells by adding the dissolved indicator to medium containing cells

Find Fluorescent Indicators for Zinc and Other Metal Ions

We offer a number of fluorescent indicators to determine polyvalent cation concentrations inside cells, to follow metal ion transport through ion channels, to make measurements in environmental samples, and more. Review Fluorescent Indicators for Zn2+ and Other Metal Ions—Section 19.7 in the Molecular Probes™ Handbook for more information on these products.

For Research Use Only. Not for human or animal therapeutic or diagnostic use.

Order Info

Shipping Condition: Room temperature

TRUSTED_SUSTAINABILITY

Specifications

Content And Storage Store in freezer -5°C to -30°C.
Detection Method Fluorescence
For Use With (Application) Zinc Indicator
For Use With (Equipment) Fluorescence Microscope
Product Type DCF Diacetate
Dye Type Newport Green DCF
Product Line Newport Green
Quantity 1 mg
Shipping Condition Room Temperature
Excitation Wavelength 505 nm
Emission Wavelength 535 nm
Show More Show Less

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only. Not for use in diagnostic procedures.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.