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  5. Tocris Bioscience™ MONNA, >98%

Tocris Bioscience™ MONNA, >98%
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Catalog No. 577050
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Catalog No. Quantity
57-705-0 50 mg
57-701-0 10 mg
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Catalog No. 57-705-0 Supplier Tocris Bioscience™ Supplier No. 5770/50
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Description

Potent TMEM16A (Anoctamin-1) blocker

MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 = 80 nM). Exhibits >100-fold selectivity for TMEM16A over bestrophin-1, CLC2 and CFTR. Induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions. Carbachol (Cat. No. 2810) induced contraction of bronchial myocytes is reduced by MONNA and intracellular calcium release is increased.

Chemical Identifiers

CAS 1572936-83-4
Molecular Formula C18H14N2O5

Specifications

Quantity 50 mg
Solubility Soluble to 100mM in DMSO
Formula Weight 338.31
Purity >98%
Molecular Weight (g/mol) 338.319
Chemical Name or Material 2-[(4-Methoxy-2-naphthalenyl)amino]-5-nitro-benzoic acid

Safety and Handling

Recommended Storage Store at 4°C
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