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Invitrogen™ Monoamine Oxidase B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115540

Catalog No. PIPA5115540


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Description

Description

Antibody detects endogenous levels of total MAOB.

MAOB (Monoamine Oxidase B), also called MAO, BRAIN, AMINE OXIDASE (FLAVIN-CONTAINING) B, is a protein that in humans is encoded by the MAOB gene. MAOB is a member of the flavin monoamine oxidase family. And it is mapped on Xp11.3. MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. Like MAOA, it also degrades dopamine. MAO-B is involved in the breakdown of dopamine, a neurotransmitter implicated in reinforcing and motivating behaviors as well as movement. MAO-B inhibition is, therefore, associated with enhanced activity of dopamine, as well as with decreased production of hydrogen peroxide, a source of reactive oxygen species.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Monoamine Oxidase B
Polyclonal
Unconjugated
MAOB
6330414K01Rik; adrenalin oxidase; amine oxidase [flavin-containing] B; HGNC:6834; MAO b; MAO, brain; MAO, platelet; Maob; MAO-B; MGC26382; monoamine oxidase B; monoamine oxidase type B; monoamine oxidase-B; RP1-201D17__B.1; tyramine oxidase
Rabbit
Affinity chromatography
RUO
109731, 25750, 4129
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide
P19643, P27338, Q8BW75
MAOB
A synthesized peptide derived from human MAOB(Accession P27338), corresponding to amino acid residues T327-A377.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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