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Tocris Bioscience™ Montelukast sodium

Catalog No. 590410
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590410 10 mg
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Catalog No. 590410 Supplier Tocris Bioscience™ Supplier No. 5904/10
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Description

CysLT1 and GPR17 antagonist

Montelukast sodium is a cysteinyl leukotriene receptor 1 (CysLT1) and GPR17 antagonist. Blocks pentylenetetrazole -induced seizures, blood brain barrier (BBB) disruption and leukocyte migration in mice. Reduces neuroinflammation, improves BBB integrity, enhances learning and memory, and restores hippocampal neurogenesis and cognitive function in aged rats. Orally active and brain penetrant.

Specifications

Chemical Name or Material 1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid sodium salt
CAS 151767-02-1
Quantity 10 mg
Target Leukotriene and Related Receptor Antagonists
Molecular Formula C35H35ClNNaO3S
Formula Weight 608.17
Purity >99%
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