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  5. Tocris Bioscience™ Montelukast sodium

Tocris Bioscience™ Montelukast sodium

Catalog No. 590410
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

CysLT1 and GPR17 antagonist

Montelukast sodium is a cysteinyl leukotriene receptor 1 (CysLT1) and GPR17 antagonist. Blocks pentylenetetrazole -induced seizures, blood brain barrier (BBB) disruption and leukocyte migration in mice. Reduces neuroinflammation, improves BBB integrity, enhances learning and memory, and restores hippocampal neurogenesis and cognitive function in aged rats. Orally active and brain penetrant.

Specifications

Chemical Name or Material 1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid sodium salt
CAS 151767-02-1
Quantity 10 mg
Target Leukotriene and Related Receptor Antagonists
Molecular Formula C35H35ClNNaO3S
Formula Weight 608.17
Purity >99%
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