Invitrogen™ MORF4 Polyclonal Antibody

Catalog No.	Quantity
PIPA520399	100 μg

Catalog No. PIPA520399 Supplier Invitrogen™ Supplier No. PA520399

Description

Rabbit Polyclonal Antibody

A suggested positive control is K562 cell lysate. PA5-20399 can be used with blocking peptide PEP-0516.

Cellular senescence is the terminal non-dividing state that normal cells enter following completion of their proliferative potential. Fusions of immortal human cell lines with each other have led to their assignment to one of four complementation groups. Mortality factor 4 (MORF4) was identified as the lead member of a family of transcription factor-like proteins that reverses this immortal phenotype. Like other members in this family, MORF4 is localized to the nucleus and possesses transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that might allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription corepressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.

Specifications

• Antigen: MORF4
• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.02% sodium azide
• Gene: MORF4
• Gene Accession No.: 0
• Gene Alias: 9130413I22Rik; AL022827; csrb; Eaf3; Esa1p-associated factor 3 homolog; FWP006; HSPC008; HSPC061; HsT17725; MEAF3; mKIAA4002; MNCb-1039; Mof4 family associated protein 1; Morf4 family associated protein 1; MORF4 family-associated protein 1; MORF4L1; MORF-related gene 15 protein; MORF-related gene on chromosome 15; MORFRG15; mortality factor 4 like 1; mortality factor 4-like protein 1; Mrfap1; mrfap1 {ECO:0000312; MRG15; Pam14; Pgr1; PP368; Protein associated with MRG of 14 kDa; protein associated with MRG, 14 kDa; protein MSL3-1; RGD:628631}; RGD1306635; S863-6; SEN1; T-cell activation protein; T-cell activation protein-related protein; TEG-189; testis expressed gene 189; testis-expressed gene 189 protein; Tex189; transcription factor-like protein MRG15
• Gene Symbols: MORF4
• Host Species: Rabbit
• Immunogen: An 18 amino acid peptide from near the amino terminus of human MORF4.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10934
• Target Species: Human, Mouse, Rat
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG