MORF4L1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 552571AP150UL

Catalog No. 50-173-6085

Description

This antibody has no cross-reaction to MORF4L2.

Cellular senescence is the terminal non-dividing state that normal cells enter following completion of their proliferative potential. Fusions of immortal human cell lines with each other have led to their assignment to one of four complementation groups. Mortality factor 4 (MORF4) was identified as the lead member of a family of transcription factor-like proteins that reverses this immortal phenotype. Like other members in this family, MORF4 is localized to the nucleus and possesses transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that might allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription corepressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.

Specifications

• Antigen: MORF4L1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MORF4L1
• Gene Alias: Eaf3, FWP006, HSPC008, HSPC061, HsT17725, MORF related gene 15 protein, MORF4L1, MORFRG15, mortality factor 4 like 1, MRG15, PP368, Protein MSL3 1, S863 6
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10933, 21761, 300891
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.55 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P60762, Q6AYU1, Q9UBU8
• Gene Symbols: Morf4l1
• Immunogen: Peptide
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG