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Invitrogen™ MORF4L2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540766

Catalog No. PIPA540766


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Description

Description

Peptide sequence: PPSGSVRKTR KNKQKTPGNG DGGSTSEAPQ PPRKKRARAD PTVESEEAFK Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%.

MORF4L2 is a protein coding gene. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MORF4L2
Polyclonal
Unconjugated
MORF4L2
2410017O14Rik; Kiaa0026; Liver regeneration-related protein LRRG00119; LRRG00119; mKIAA0026; Morf4l2; MORFL2; MORF-related gene X; MORF-related gene X protein; mortality factor 4 like 2; mortality factor 4-like protein 2; MRGX; MSL3-2 protein; OTTHUMP00000023756; protein MSL3-2; RP5-1055C14.2; Sid 393; Sid393; Sid393p; transcription factor-like protein Mrgx
Rabbit
Protein A
RUO
9643
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 2% sucrose and 0.09% sodium azide
Q15014
MORF4L2
Synthetic peptide directed towards the N-terminal of human MORF4L2 (aa 67-116).
100 μL
Primary
Human
Antibody
IgG
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