Invitrogen™ MORF4L2 Polyclonal Antibody

Catalog No.	Quantity
PIPA584184	100 μL

Catalog No. PIPA584184 Supplier Invitrogen™ Supplier No. PA584184

Description

Rabbit Polyclonal Antibody

Immunogen sequence: MSSRKQGSQP RGQQSAEEEN FKKPTRSNMQ RSKMRGASSG KKTAGPQQKN LEPALPGRWG GRSAENPPSG SVRKTRK Highest antigen sequence indentity to the following orthologs: Rat - 90%, Mouse - 90%.

MORF4L2 is a protein coding gene. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.

Specifications

• Antigen: MORF4L2
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: MORF4L2
• Gene Accession No.: Q15014
• Gene Alias: 2410017O14Rik; Kiaa0026; Liver regeneration-related protein LRRG00119; LRRG00119; mKIAA0026; Morf4l2; MORFL2; MORF-related gene X; MORF-related gene X protein; mortality factor 4 like 2; mortality factor 4-like protein 2; MRGX; MSL3-2 protein; OTTHUMP00000023756; protein MSL3-2; RP5-1055C14.2; Sid 393; Sid393; Sid393p; transcription factor-like protein Mrgx
• Gene Symbols: MORF4L2
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human MORF4L2. Recombinant protein control fragment (Product #RP-101246).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9643
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG