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Invitrogen™ MORF4L2 Polyclonal Antibody
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Catalog No. PIPA596724
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100 μL
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PIPA596724 100 μL
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Catalog No. PIPA596724 Supplier Invitrogen™ Supplier No. PA596724
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Description

Rabbit Polyclonal Antibody

Positive Samples: Cellular Location: Nucleus Immunogen sequence: MSSRKQGSQP RGQQSAEEEN FKKPTRSNMQ RSKMRGASSG KKTAGPQQKN LEPALPGRWG GRSAENPPSG SVRKTRKNKQ KTPGNGDGGS TSEAPQPPRK KRARADPTVE SEEAFKNRME VKVKIPEELK PWLVEDWDLV TRQKQLFQLP AKKNVDAILE EYANCKKSQG NVDNKEYAVN EVVAGIKEYF NVMLGTQLLY KFERPQYAEI LLAHPDAPMS QVYGAPHLLR LFVRIGAMLA YTPLDEKSLA LLLGYLHDFL KYLAKNSASL FTASDYKVAS AE.

MORF4L2 is a protein coding gene. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MORF4L2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.66 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MORF4L2
Gene Accession No. Q15014, Q6QI89, Q9R0Q4
Gene Alias 2410017O14Rik; Kiaa0026; Liver regeneration-related protein LRRG00119; LRRG00119; mKIAA0026; Morf4l2; MORFL2; MORF-related gene X; MORF-related gene X protein; mortality factor 4 like 2; mortality factor 4-like protein 2; MRGX; MSL3-2 protein; OTTHUMP00000023756; protein MSL3-2; RP5-1055C14.2; Sid 393; Sid393; Sid393p; transcription factor-like protein Mrgx
Gene Symbols MORF4L2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-282 of human MORF4L2 (NP_0011358901).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 317413, 56397, 9643
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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