Invitrogen™ MORF4L2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596724

Catalog No. PIPA596724

Description

Positive Samples: Cellular Location: Nucleus Immunogen sequence: MSSRKQGSQP RGQQSAEEEN FKKPTRSNMQ RSKMRGASSG KKTAGPQQKN LEPALPGRWG GRSAENPPSG SVRKTRKNKQ KTPGNGDGGS TSEAPQPPRK KRARADPTVE SEEAFKNRME VKVKIPEELK PWLVEDWDLV TRQKQLFQLP AKKNVDAILE EYANCKKSQG NVDNKEYAVN EVVAGIKEYF NVMLGTQLLY KFERPQYAEI LLAHPDAPMS QVYGAPHLLR LFVRIGAMLA YTPLDEKSLA LLLGYLHDFL KYLAKNSASL FTASDYKVAS AE.

MORF4L2 is a protein coding gene. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.

Specifications

• Antigen: MORF4L2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MORF4L2
• Gene Alias: 2410017O14Rik; Kiaa0026; Liver regeneration-related protein LRRG00119; LRRG00119; mKIAA0026; Morf4l2; MORFL2; MORF-related gene X; MORF-related gene X protein; mortality factor 4 like 2; mortality factor 4-like protein 2; MRGX; MSL3-2 protein; OTTHUMP00000023756; protein MSL3-2; RP5-1055C14.2; Sid 393; Sid393; Sid393p; transcription factor-like protein Mrgx
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 317413, 56397, 9643
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.66 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q15014, Q6QI89, Q9R0Q4
• Gene Symbols: MORF4L2
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-282 of human MORF4L2 (NP_0011358901).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov