Mortality factor 4-like protein 1 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-7843	100 μL

Catalog No. 50-198-7843 Supplier Bioss Supplier No. BS7576R

Description

Rabbit Polyclonal Antibody

Cellular senescence is the terminal non-dividing state that normal cells enter following completion of their proliferative potential. Fusions of immortal human cell lines with each other have led to their assignment to one of four complementation groups. Mortality factor 4 (MORF4) was identified as the lead member of a family of transcription factor-like proteins that reverses this immortal phenotype. Like other members in this family, MORF4 is localized to the nucleus and possesses transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that might allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription corepressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.

Specifications

• Antigen: Mortality factor 4-like protein 1
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: MORF4
• Gene Alias: SEN1
• Gene Symbols: MORF4
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human Mortality factor 4-like protein 1/SEN1.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10934
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG