Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. 89111362

ABCB1, Mouse, Clone: MRK16, Abnova™

Catalog No. 89111362 Shop All Abnova Corporation Products
Change view
Click to view available options
Quantity:
150 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
89-111-362 150 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. 89-111-362 Supplier Abnova Corporation Supplier No. MAB3345

Description

Mouse monoclonal antibody raised against native ABCB1.

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq

Specifications

Antigen ABCB1
Applications Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Classification Monoclonal
Clone MRK16
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against native ABCB1.
Dilution Immunoprecipitation (25 ug/mL-50 ug/mL) Immunohistochemistry (0.1-10 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS
Gene ABCB1
Gene Alias ABC20/CD243/CLCS/GP170/MDR1/MGC163296/P-GP/PGY1
Gene Symbols ABCB1
Host Species Mouse
Immunogen Native purified ABCB1 from Adriamycin-resistant human myelogenous leukemia K-562/ADM cells.
Quantity 150 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5243
Test Specificity Monoclonal antibody MRK16 recognizes a surface epitope of the 170 KDa human P-glycoprotein. This antibody reacts with human cortical adenomas but does not react with eochromocytoma, non-functioning cortical adenoma or myolipoma of the adrenal. Does not react with mouse.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG2a
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.