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ABCC8, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89105538 Shop All Abnova Corporation Products
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89-105-538 50 μL
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Catalog No. 89-105-538 Supplier Abnova Corporation Supplier No. H00006833A01
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Description

Mouse polyclonal antibody raised against a partial recombinant ABCC8.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with noninsulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however, the transcript variants have not been fully described. [provided by RefSeq

Sequence: SEFLSSAEIREEQCAPHEPTPQGPASKYQAVPLRVVNRKRPAREDCRGLTGPLQSLVPSADGDADNCCVQIMGGYFTWTPDGIPTLSNITIRIPRGQLTM

Specifications

Antigen ABCC8
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant ABCC8.
Formulation 50% glycerol
Gene ABCC8
Gene Accession No. NM_000352
Gene Alias ABC36/HHF1/HI/HRINS/MRP8/PHHI/SUR/SUR1/TNDM2
Gene Symbols ABCC8
Host Species Mouse
Immunogen ABCC8 (NP_000343, 611 a.a. to 710 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6833
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Antisera
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For Research Use Only

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