ABCG2, Mouse, Clone: 1H2, Abnova™

Mouse monoclonal antibody raised against partial recombinant ABCG2.

Supplier:  Abnova Corporation MAB10479

Catalog No. 89-108-663

Description

The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq

Specifications

• Antigen: ABCG2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunofluorescence (1:200-1:1000) The optimal working dilution should be determined by the end user.
• Gene: ABCG2
• Gene Symbols: ABCG2
• Immunogen: Recombinant protein corresponding to human ABCG2.
• Regulatory Status: RUO
• Gene ID (Entrez): 9429
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Immunofluorescence, Western Blot
• Clone: 1H2
• Description: Mouse monoclonal antibody raised against partial recombinant ABCG2.
• Formulation: In ascites (0.03% sodium azide)
• Gene Alias: ABC15/ABCP/BCRP/BCRP1/BMDP/CD338/CDw338/EST157481/MGC102821/MRX/MXR/MXR1
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Monkey, Mouse
• Form: Liquid