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ABCG2, Mouse, Clone: 3G8, Abnova™

Catalog No. 89108662 Shop All Abnova Corporation Products
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89-108-662 100 μL
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Catalog No. 89-108-662 Supplier Abnova Corporation Supplier No. MAB10478
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Description

Mouse monoclonal antibody raised against partial recombinant ABCG2.

The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq

Specifications

Antigen ABCG2
Applications ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Classification Monoclonal
Clone 3G8
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant ABCG2.
Dilution ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
Formulation In ascites (0.03% sodium azide)
Gene ABCG2
Gene Alias ABC15/ABCP/BCRP/BCRP1/BMDP/CD338/CDw338/EST157481/MGC102821/MRX/MXR/MXR1
Gene Symbols ABCG2
Host Species Mouse
Immunogen Recombinant protein corresponding to human ABCG2.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9429
Target Species Human, Monkey, Mouse
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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